Trastuzumab deruxtecan

trastuzumab  trastuzumab emtansine continued to improve invasive disease–free survival and overall survival compared with trastuzumab in patients Comment: Trastuzumab is a humanized IgG1κ monoclonal antibody targeting HER2 Annotated peptide sequences for this antibody are available from its IMGTmAb-DB

Scottish Medicines Consortium decisions For trastuzumab · SMC No 92813 Trastuzumab for the treatment of adult patients trastuzumab Early breast cancer Herceptin is indicated for the treatment of patients with HER2-positive early breast cancer: following surgery

Trastuzumab has also been shown to penetrate an impaired blood–brain barrier to a limited degree, such as during radiotherapy, and intrathecal delivery of Common side effects of pertuzumab and trastuzumab · Risk of infection · Bruising and bleeding · Anaemia · Effects on the heart